Disease related

anti-Arginase-1 mouse monoclonal, IHC400, purified

Cat. No: 691751

Available, delivery time 1-7 days

$588.00*

Key Features
  • Mouse monoclonal
  • Suitable for IHC
  • Reacts with human
  • Isotype: IgG2b
Product description
Quantity 1 ml
Antibody Type Monoclonal
Host Mouse
Isotype IgG2b
Conjugate Unconjugated
Application IHC
Purification Affinity chromatography
Reactivity Human
Storage 2-8°C
Intended use Research use only
Clone IHC400
Immunogen Recombinant Human Arginase-1
Formulation Tris pH 7.3-7.7 with 1% BSA and 0.09% sodium azide
UniprotID P05089 (Human)
Synonym Arginase-1, EC 3.5.3.1, Liver-type arginase, Type I arginase, ARG1

Applications
Tested applications Tested dilutions
Immunohistochemistry (IHC) - paraffin 1:50-1:200 (microwave treatment recommended)
Background
Arginase-1, encoded by the ARG1 gene, is a cytosolic metalloenzyme expressed predominantly in hepatocytes. Arginase-1 plays a key role in the urea cycle by catalyzing the hydrolysis of arginine to ornithine and urea. Argininemia is an inherited autosomal recessive disorder characterized by a buildup of arginine and ammonia in the blood. Anti-Arginase-1 is highly specific for hepatocytes, and is therefore a sensitive and specific marker of benign and malignant hepatic tumours.
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