Epitope mapped
Diagnostic marker

anti-Cyclin-Dependent Kinase 4 mouse monoclonal, DCS-156, lyophilized, purified

Cat. No: 61096

Available, delivery time 1-7 days

$200.00*

Key Features
  • Mouse monoclonal
  • Suitable for WB
  • Reacts with human, mouse and rat
  • Isotype: IgG1
Product description
Quantity 50 µg
Antibody Type Monoclonal
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Application WB
Purification Affinity chromatography
Reactivity Human, Mouse, Rat
Storage before reconstitution 2-8°C until indicated expiry date
Storage after reconstitution Up to 3 months at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles
Intended use Research use only
Clone DCS-156
Immunogen Human recombinant full-length cdk4 polypeptide
Concentration 50 µg/ml after reconstitution with 1ml dist. water
Formulation Lyophilized; reconstitute in 1 ml dist. water (final solution contains 0.09% sodium azide, 0.5% BSA in PBS buffer, pH 7.4)
UniprotID P11802 (Human),P30285 (Mouse),P35426 (Rat)
Synonym Cyclin-dependent kinase 4, EC 2.7.11.22, Cell division protein kinase 4, PSK-J3, CDK4
Applications
Tested applications Tested dilutions
Western Blot (WB) 1:50-1:500
Background

DCS-156 reacts specifically with cdk4 protein present predominantly in G1 phase of cell cycle; it does not cross-react with cyclins. In immunohistochemical application on frozen sections of head and neck carcinoma (oropharynx and hypopharynx carcinoma) and cervix DCS-156 shows distinct nuclear staining, especially in tumor areas of enhanced proliferation.
Epitope recognized: aa 270-290.

References/Publications (1)
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