anti-Keratin K77 guinea pig polyclonal, serum

Cat. No: GP-K77

Available, delivery time 1-7 days

$311.00*

Key Features
  •     Guinea pig polyclonal
  •     Suitable for IHC and WB
  •     Reacts with human
Product description
Quantity 100 µl
Antibody Type Polyclonal
Host Guinea pig
Conjugate Unconjugated
Application IHC, WB
Purification Stabilized antiserum
Reactivity Human
No reactivity Mouse
Storage Short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles
Intended use Research use only
Immunogen Synthetic peptide from human K77(K1b): RVY STS SSA GSG GGS-C
Formulation Contains 0.09% sodium azide and 0.5% BSA
UniprotID Q7Z794 (Human)
Synonym Keratin, type II cytoskeletal 1b, Cytokeratin-1B, CK-1B, Keratin-77, K77, Type-II keratin Kb39, KRT77, KRT1B
Note Centrifuge prior to opening
Applications
Tested applications Tested dilutions
Immunohistochemistry (IHC) - frozen 1:1,000
Immunohistochemistry (IHC) - paraffin 1:1,000 (microwave treatment recommended)
Western Blot (WB) Assay dependent
Background
K77 (formerly K1b) is closely related to K1, but, in adult humans, it is exclusively expressed in luminal duct cells of eccrine sweat glands. The secretory gland is negative as the peripheral cells of the duct. Furthermore, K77 is expressed in suprabasal fetal epidermis, where it appears slightly subsequent to K1. This expression order is also found in conventional and organotypic cultures of human keratinocytes. Ultrastructural investigations show that in contrast to murine K77 intermediate filaments, those of the human ortholog are not attached to desmosomes. After birth, K77 disappears without consequences from human epidermis.
References/Publications (1)
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FAQs
Lyophilized antibodies can be stored at 2-8°C until expiration.
Most of our liquid antibodies and reconstituted lyophilized antibodies may be stored for short term storage (up to 3 month) at 2-8°C. For long term storage we recommend to store the antibody at -20°C in aliquots. Please avoid freeze and thaw cycles.
Most of our conjugated antibodies should be stored at 2-8°C.
The individual storage conditions are mentioned on the datasheet.

anti-guinea pig IgG goat polyclonal, HRP conjugate
Cat. No: 90001
  • Goat polyclonal
  • Suitable for ELISA and WB
  • Reacts with guinea pig

$109.00*