Disease related

anti-CD48 mouse monoclonal, 156-4H9, purified

Cat. No: 691590

Available, delivery time 1-7 days

$425.00*

Key Features
  • Mouse monoclonal
  • Suitable for FACS, ICC/IF and IHC
  • Reacts with human
  • Isotype: IgG1 kappa
Product description
Quantity 1 ml (100 µg/ml)
Antibody Type Monoclonal
Host Mouse
Isotype IgG1 kappa
Conjugate Unconjugated
Application FACS, ICC/IF, IHC
Purification Affinity chromatography
Reactivity Human
Storage 2-8°C
Intended use Research use only
Clone 156-4H9
Immunogen Stimulated human PBL
Concentration 100 µg/ml
Formulation PBS with 0.02% sodium azide
UniprotID P09326 (Human)
Synonym CD48 antigen, B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, Leukocyte antigen MEM-102, SLAM family member 2, SLAMF2, Signaling lymphocytic activation molecule 2, TCT.1, CD antigen CD48, CD48, BCM1, BLAST1
Applications
Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) 1:100-1:200 (0.5-1.0 µg/ml)
Immunohistochemistry (IHC) - frozen 1:50-1:100 (1-2 µg/ml)
Flow Cytometry (FACS) 0.5-1.0 µg/million cells in 0.1 ml
Background

CD48 is a 45 kDa glycosyl phophatidyl-inositol (GPI)-anchored cell surface protein, highly expressed on lymphocytes and monocytes and weakly on granulocytes. Platelets, fibroblasts, epithelium and endothelium are negative. CD48 has a cellular function in adhesion via its receptor CD2 and a role in gamma/delta T-cell recognition as an accessory molecule and forms one of the markers for detecting the GPI anchoring defect in patients with paroxysmal nocturnal hemoglobinuria (PNH). 156-4H9 was typed in Kobe, Japan at the VIth International Workshop on human leucocyte differentiation antigens.

Positive control: Daudi, JY, Raji, Jurkat, and human lymphocytes. Human lymph node and tonsil.

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