anti-Factor VIIIc mouse monoclonal, MH104, lyophilized, purified
- Mouse monoclonal
- Suitable for ELISA, IHC and WB
- Reacts with human
- Isotype: IgG2a
|Application||ELISA, IHC, WB|
|Storage before reconstitution||2-8°C until indicated expiry date|
|Storage after reconstitution||Up to 3 months at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles|
|Intended use||Research use only|
|Immunogen||Human factor VIII antigen|
|Concentration||500 µg/ml after reconstitution with 1 ml dist. water
|Formulation||Lyophilized; reconstitute in 1 ml dist. water (final solution contains 0.09% sodium azide, 0.5% BSA in PBS buffer, pH 7.4)|
|Tested applications||Tested dilutions|
|Immunohistochemistry (IHC) - frozen||Assay dependent|
|Western Blot (WB)||Assay dependent|
MH104 is specific for human factor VIIIc, a 300 kDa protein present in plasma in a complex with von Willebrandt factor. Involved in the clotting cascade (activated by thrombin) by forming a complex with factor IXa, calcium, and phospholipids.
Polypeptide reacting: Factor VIIIc protein (epitope localization: intact 83 kDa light chain).
Disorders specifically detected: Elevated levels of factor VIII have been associated with acute and chronic liver diseases, vascular disorders, diabetes and with acute-phase reactions.
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