Disease related

anti-GnRH-receptor mouse monoclonal, F1G4, purified

Cat. No: 691685

Available, delivery time 1-7 days

$425.00*

Key Features
  • Mouse monoclonal
  • Suitable for ELISA, IHC and WB
  • Reacts with human and rat
  • Isotype: IgG1 kappa
Product description
Quantity 1 ml (100 µg/ml)
Antibody Type Monoclonal
Host Mouse
Isotype IgG1 kappa
Conjugate Unconjugated
Application ELISA, IHC, WB
Purification Affinity chromatography
Reactivity Human, Rat
Storage 2-8°C
Intended use Research use only
Clone F1G4
Immunogen BSA-conjugated peptide corresponding to amino acids 1-29 (MANSASPEQNQHCSAINNSIPLMQGNLPY) of human GnRH receptor extracellular domain
Concentration 100 µg/ml
Formulation PBS with 0.02% sodium azide
UniprotID Q96P88 (Human)
Synonym Putative gonadotropin-releasing hormone II receptor, GnRH II receptor, GnRH-II-R, Type II GnRH receptor, GNRHR2
Applications
Tested applications Tested dilutions
Immunohistochemistry (IHC) - frozen 1:50-1:100 (1-2 µg/ml)
Immunohistochemistry (IHC) - paraffin 1:50-1:100 (1-2 µg/ml; microwave treatment in 10 mM Tris with 1mM EDTA pH 9.0 recommended)
ELISA Assay dependent
Western Blot (WB) 1:50-1:100 (1-2 µg/ml)
Background

F1G4 reacts with GnRH receptors in the anterior pituitary. GnRH stimulates the gonadotrophs of the anterior pituitary to secrete luteinising hormone (LH) as well as follicle-stimulating hormone (FSH). The receptor contains seven hydrophobic transmembrane domains connected by hydrophilic extracellular, and intracellular loops characteristic of G protein couple receptors. Some cancers like ovarian and breast cancers sometimes carry.

Positive control: Human pituitary gland, ovarian and breast cancers.

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