anti-Keratin K16 guinea pig polyclonal, serum
- Guinea pig polyclonal
- Suitable for IHC
- Reacts with human and mouse
|Storage||Short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles|
|Intended use||Research use only|
|Immunogen||Synthetic peptide of human keratin K16 (formerly also designated cytokeratin 16; C-KE QSS SSF SQG QSS), coupled to KLH|
|Formulation||Contains 0.09% sodium azide and 0.5% BSA|
|Synonym||Keratin, type I cytoskeletal 16, Cytokeratin-16, CK-16, Keratin-16, K16, KRT16, KRT16A|
|Note||Centrifuge prior to opening|
|Tested applications||Tested dilutions|
|Immunohistochemistry (IHC) - frozen||1:100-1:200|
|Immunohistochemistry (IHC) - paraffin||1:100-1:200 (microwave treatment recommended)|
MW 48,000 (pI 5.1) intermediate filament polypeptide, keratin K16, detected by immunohistochemistry in psoriatic skin, in the rete ridges of foot sole epidermis, in tongue, esophagus, exocervix and in squamous cell carcinoma of skin, tongue and cervix. In the hair follicle, staining was restricted to the outer root sheath.
Completely non-reactive were cells of non-stratified epithelia (e.g. liver, colon).
Positive control: rete ridges of human foot sole epidermis, psoriatic skin.
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