Disease related

anti-LRP1 (85kDa) mouse monoclonal, 8B8, lyophilized w/o sodium azide, purified

Cat. No: 61067

Available, delivery time 1-7 days

$293.00*

Key Features
  • Mouse monclonal
  • Suitable for FACS, ICC/IF, IHC and WB
  • Reacts with hamster, human, mouse, rabbit and rat
  • Isotype: IgG1
Product description
Quantity 50 µg
Antibody Type Monoclonal
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Application FACS, ICC/IF, IHC, WB
Purification Affinity chromatography
Reactivity Hamster, Human, Mouse, Rabbit, Rat
Storage before reconstitution 2-8°C until indicated expiry date
Storage after reconstitution Up to 3 months at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles
Intended use Research use only
Clone 8B8
Immunogen Human LRP/alpha-2MR
Concentration 50 µg/ml after reconstitution with 1 ml dist. water
Formulation Lyophilized; reconstitute in 1 ml dist. water (final solution contains 0.5% BSA in PBS buffer, pH 7.4)
Applications
Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) Assay dependent
Immunohistochemistry (IHC) - frozen 1:20
Immunohistochemistry (IHC) - paraffin 1:20 (microwave treatment recommended)
Flow Cytometry (FACS) Assay dependent
Western Blot (WB) Assay dependent
Background

8B8 specifically reacts with the 85 kDa beta-chain of human LRP/alpha-2MR which is expressed in a restricted spectrum of cell types (Herz & Strickland 2001). A strong immunohistochemical reaction is seen in hepato-cytes, tissue macrophages, subsets of neurones and as-trocytes in the central nervous system, fibroblasts, smooth muscle cells, and monocyte-derived foam cells in athero-sclerotic lesions in the arterial wall. The antibody can also be used for the characterization of a subset of myelo-monocytic subtypes of chronic and acute leukemia (CD 91).

Herz J and Strickland DK: LRP, a multifunctional scavanger and signaling receptor. J. Clin. Invest. 108, 779-784 (2001)

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anti-LRP1 (85kDa) mouse monoclonal, 5A6, lyophilized w/o sodium azide, purified
Cat. No: 61066
  • Mouse monoclonal
  • Suitable for FACS, IHC and WB
  • Reacts with hamster, human, mouse, rabbit and rat
  • Isotype: IgG2b

$293.00*
anti-LRP1 (515kDa) mouse monoclonal, 8G1, lyophilized w/o sodium azide, purified
Cat. No: 61065
  • Mouse monoclonal
  • Suitable for FACS, IHC and WB
  • Reacts with human
  • Isotype: IgG1

$293.00*