Diagnostic marker

anti-Myogenin mouse monoclonal, IHC631, purified

Cat. No: 691732

Available, delivery time 1-7 days

$588.00*

Key Features
  • Mouse monoclonal
  • Suitable for IHC
  • Reacts with human
  • Isotype: IgG1 kappa
Product description
Quantity 1 ml
Antibody Type Monoclonal
Host Mouse
Isotype IgG1 kappa
Conjugate Unconjugated
Application IHC
Purification Affinity chromatography
Reactivity Human
Storage 2-8°C
Intended use Research use only
Clone IHC631
Immunogen Recombinant Human Myogenin
Formulation Tris pH 7.3-7.7 with 1% BSA and 0.09% sodium azide
UniprotID P15173 (Human)
Synonym Myogenin, Class C basic helix-loop-helix protein 3, bHLHc3, Myogenic factor 4, Myf-4, MYOG, BHLHC3, MYF4
Applications
Tested applications Tested dilutions
Immunohistochemistry (IHC) - paraffin 1:50-1:200 (microwave treatment recommended)
Background
Myogenin belongs to a family of myogenic transcription factors, including MyoD, Myf5, and MRF4, which are critical in muscle development. Myogenin is found strictly in cells of skeletal muscle origin, and is therefore used as a biomarker for tumours of the muscle lineage, including alveolar rhabdomyosarcomas. Anti-Myogenin staining may occur in Wilms' tumour, and it labels the nuclei of myoblasts in developing muscle tissue. It is also expressed in some leiomyosarcomas.
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