Diagnostic marker

anti-TTF-1 mouse monoclonal, 8G7G3/1, supernatant

Cat. No: 16108

Available, delivery time 1-7 days

$306.00*

Key Features
  • Mouse monoclonal
  • Suitable for ICC/IF, IHC on frozen and paraffin sections and WB
  • Reacts with human mouse and rat
  • Isotype: IgG1
Product description
Quantity 1 ml
Antibody Type Monoclonal
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Application ICC/IF, IHC, WB
Purification Hybridoma cell culture supernatant
Reactivity Human, Mouse, Rat
Storage Short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles
Intended use Research use only
Clone 8G7G3/1
Immunogen Rat TTF-1 recombinant protein
Formulation Contains 0.09 % sodium azide
UniprotID P43699 (Human),Q62187 (Mouse),P23441 (Rat)
Synonym Homeobox protein Nkx-2.1, Homeobox protein NK-2 homolog A, Thyroid nuclear factor 1, Thyroid transcription factor 1, TTF-1, Thyroid-specific enhancer-binding protein, T/EBP, NKX2-1, NKX2A, TITF1, TTF1
Note Centrifuge prior to opening
Applications
Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) Assay dependent
Immunohistochemistry (IHC) - frozen 1:10-1:20
Immunohistochemistry (IHC) - paraffin 1:10-1:20 (microwave treatment recommended)
Western Blot (WB) Assay dependent
Background

The antibody recognizes a 40 kDa protein (e.g. in nuclear extracts of human H345 cells), identified as thyroid transcription factor 1 (TTF-1), selectively expressed in the lung, thyroid and diencephalon. The antigen has been localized in the nucleus.

Tumors specifically detected: the antibody is useful in the classification of thyroid and lung tumors.

Positive control: normal thyroid or lung.

References/Publications (3)
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