anti-Vasoactive Intestinal Peptide guinea pig polyclonal, serum

Cat. No: 16071

Available, delivery time 1-7 days

$514.00*

Key Features
  • Guinea pig polyclonal
  • Suitable for IHC on frozen and paraffin sections
  • Reacts with cat, guinea pig, human, pig, rabbit and rat
Product description
Quantity 50 µl (lyoph.)
Antibody Type Polyclonal
Host Guinea pig
Conjugate Unconjugated
Application IHC
Purification Undiluted antiserum
Reactivity Cat, Guinea pig, Human, Pig, Rabbit, Rat
Storage before reconstitution 2-8°C until indicated expiry date
Storage after reconstitution Up to 3 months at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles
Intended use Research use only
Immunogen Synthetic human VIP (Peninsula, #7161)
Formulation Lyophilized; reconstitute in 100 µl dist. water
UniprotID A0A5F5XTM9 (Cat, Felis silvestris catus), P04566 (Guinea pig), P01282 (Human), P01284 (Pig), P32649 (Rabbit), P01283 (Rat)
Synonym VIP peptides [Cleaved into: Intestinal peptide PHV-42, Peptide histidine valine 42; Intestinal peptide PHM-27, Peptide histidine methioninamide 27; Vasoactive intestinal peptide, VIP, Vasoactive intestinal polypeptide], VIP
Applications
Tested applications Tested dilutions
Immunohistochemistry (IHC) - frozen 1:1,000-1:2,000
Immunohistochemistry (IHC) - paraffin 1:1,000-1:2,000 (microwave treatment recommended)
Background

VIP is localized in nerve fibers of the central and peripheral nervous system, and is probably acting as a neurotransmitter. Smooth muscle relaxation, vasodilation and secretion from exocrine glands are some of the effects of VIP. The Verner-Morrison or Watery Diarrhea Hypokaliemia and Achlorhydria (WDHA) syndrome is a characteristic clinical syndrome associated with overproduction of VIP from endocrine tumors. These VIP-producing tumors are usually neuroblastomas of endocrine tumors in the pancreas.
Absorption with 10-100 ug immunogen per ml diluted antiserum abolishes the staining, while PHI does not.
Positive control: Stefanini-fixed frozen sections of rat intestine.

References/Publications (2)
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  • Rabbit polyclonal
  • Suitable for IHC on frozen and paraffin sections
  • Reacts with cat, human, pig and rat

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