anti-Vasoactive Intestinal Peptide guinea pig polyclonal, serum
- Guinea pig polyclonal
- Suitable for IHC on frozen and paraffin sections
- Reacts with cat, guinea pig, human, pig, rabbit and rat
|Quantity||50 µl (lyoph.)|
|Reactivity||Cat, Guinea pig, Human, Pig, Rabbit, Rat|
|Storage before reconstitution||2-8°C until indicated expiry date|
|Storage after reconstitution||Up to 3 months at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles|
|Intended use||Research use only|
|Immunogen||Synthetic human VIP (Peninsula, #7161)|
|Formulation||Lyophilized; reconstitute in 100 µl dist. water|
|UniprotID||A0A5F5XTM9 (Cat, Felis silvestris catus), P04566 (Guinea pig), P01282 (Human), P01284 (Pig), P32649 (Rabbit), P01283 (Rat)|
|Synonym||VIP peptides [Cleaved into: Intestinal peptide PHV-42, Peptide histidine valine 42; Intestinal peptide PHM-27, Peptide histidine methioninamide 27; Vasoactive intestinal peptide, VIP, Vasoactive intestinal polypeptide], VIP|
|Tested applications||Tested dilutions|
|Immunohistochemistry (IHC) - frozen||1:1,000-1:2,000|
|Immunohistochemistry (IHC) - paraffin||1:1,000-1:2,000 (microwave treatment recommended)|
VIP is localized in nerve fibers of the central and peripheral nervous system, and is probably acting as a neurotransmitter. Smooth muscle relaxation, vasodilation and secretion from exocrine glands are some of the effects of VIP. The Verner-Morrison or Watery Diarrhea Hypokaliemia and Achlorhydria (WDHA) syndrome is a characteristic clinical syndrome associated with overproduction of VIP from endocrine tumors. These VIP-producing tumors are usually neuroblastomas of endocrine tumors in the pancreas.
Absorption with 10-100 ug immunogen per ml diluted antiserum abolishes the staining, while PHI does not.
Positive control: Stefanini-fixed frozen sections of rat intestine.
Q & A's
0 of 0 reviews