anti-delta Catenin guinea pig polyclonal, serum
- Guinea pig polyclonal
- Suitable for ICC/IF, IHC and WB
- Reacts with bovine, human, mouse and rat
|Application||ICC/IF, IHC, WB|
|Reactivity||Bovine, Human, Mouse, Rat|
|Storage||Short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles|
|Intended use||Research use only|
|Immunogen||Synthetic peptide J7 (corresponding to aa 1175-1192), coupled to KLH|
|Formulation||Contains 0.09% sodium azide and 0.5% BSA|
|Note||Centrifuge prior to opening|
|Tested applications||Tested dilutions|
|Immunocytochemistry (ICC)/ Immunofluorescence (IF)||1:100|
|Immunohistochemistry (IHC) - frozen||1:100|
|Immunohistochemistry (IHC) - paraffin||1:100 (microwave treatment recommended)|
|Western Blot (WB)||1:2,500|
The antibody reacts specifically with neurojungin (delta-catenin, a unique 160 kD polypeptide of the plakoglobin / armadillo protein family) present in adhering type junctions in the nervous system, primarily expressed in the brain. Delta-catenin also binds to presenilin-1, mutations of this protein are described to play a role in familial Alzheimer’s disease. No cross-reaction with other members of the armadillo / plakoglobin protein family.
Polypeptide reacting: Neurojungin (delta-catenin), 160 kD polypeptide.
Reactivity on cultured cell lines: Murine cell line A1B2, stably transfected with neurojungin cDNA.
Positive control: Murine brain, retina.
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