anti-Calcitonin Gene Related Peptide rabbit polyclonal, serum

Cat. No: 16008

Available, delivery time 1-7 days

$475.00*

Key Features
  • Rabbit polyclonal
  • Suitable for ICC/IF and IHC
  • Reacts with human and rat
Product description
Quantity 50 µl
Antibody Type Polyclonal
Host Rabbit
Conjugate Unconjugated
Application ICC/IF, IHC
Purification Undiluted antiserum
Reactivity Human, Rat
Storage before reconstitution 2-8°C until indicated expiry date
Storage after reconstitution Up to 3 months at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles
Intended use Research use only
Immunogen Calcitonin gene-related peptide (synthetic, rat, #6006, Peninsula), conjugated to BSA
Formulation Lyophilized; reconstitute in 100 µl dist. water
UniprotID P06881 (Human)
Synonym Calcitonin gene-related peptide 1, Alpha-type CGRP, Calcitonin gene-related peptide I, CGRP-I, CALCA, CALC1
Applications
Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) 1:800-1:1,500
Immunohistochemistry (IHC) - frozen 1:1,000-1:2,000
Immunohistochemistry (IHC) - paraffin 1:1,000-1:2,000 (microwave treatment recommended)
Background

The CGRP-sequence was predicted from the corresponding mRNA. CGRP is present in the C-cells of the thyroid and in nerves, in both brain and periphery, particularly within the sensory system. CGRP is a potent vasodilator, probably involved in neurogenic inflammation. Medullary carcinomas of the thyroid contain large amounts of CGRP. Absorption with 10-100 ug CGRP per ml diluted antiserum abolishes the staining while calcitonin, substance P and Neurokinin A do not. The antiserum cross-reacts with amylin.

Positive control: frozen sections of rat colon.

References/Publications (3)
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