Disease related

anti-Lamin A + C mouse monoclonal, R27, supernatant

Cat. No: 651138

Available, delivery time 1-7 days

$245.00*

Key Features
  • Mouse monoclonal
  • Suitable for ICC/IF and WB
  • Reacts with bovine, human, mouse, trout, xenopus and zebrafish
  • Isotype: IgM
Product description
Quantity 5 ml
Antibody Type Monoclonal
Host Mouse
Isotype IgM
Conjugate Unconjugated
Application ICC/IF, WB
Purification Hybridoma cell culture supernatant
Reactivity Bovine, Human, Mouse, Trout, Xenopus, Zebrafish
Storage Short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles
Intended use Research use only
Clone R27
Immunogen Nuclear pore complex-lamina fraction of bovine liver
Formulation Contains 0.09% sodium azide
Applications
Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) Ready-to-use
Western Blot (WB) Assay dependent
Background

The monoclonal antibody decorates the lamina, i.e. the nucleoplasmic layer coating the nuclear envelope.
Mutations in lamin A have been shown to cause Hutchinson-Gilford progeria syndrome in human and mouse and other laminopathies (for review see Burke & Stewart, 2002).

Polypeptides reacting: Lamin isotypes A and C (Mr 60 - 75 kDa); meiotic lamin C2

Reactivity in cultured cell lines: RV-SMC (rat vascular smooth muscle cells)















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FAQs
The concentration of unpurified supernatant, ascites, unpurified guinea pig serum and unpurified rabbit serum is not determined.
The concentration of purified antibodies is mentioned on the datasheet.
For prediluted antibodies the concentration may vary from lot to lot. The concentration of these antibodies is not mentioned on the datasheet and can be requested at support@progen.com.

PROGEN offers different formats for mouse monoclonal antibodies.  Different antibodies may not be offered in each format, the following are all possible formats:
  1. Supernatant and supernatant concentrate: This format contains hybridoma cell culture supernatant. The antibody is not purified and the antibody concentration is not determined. The antibody concentration may vary from lot to lot. Therefore we recommend to titrate the optimal concentration for the application used for each new lot.
  2. Lyophilized, purified: This format contains purified antibody in lyophilized form. The reconstitution of this antibody is described in the datasheet. The buffer composition after reconstitution is also mentioned on the datasheet. 
  3. Liquid, purified: This format contains purified antibody in liquid format. The concentration is mentioned on the datasheet. 
  4. Prediluted, purified: This format contains purified antibody in liquid format. Most antibodies in this format are diluted to be ready-to-use for IHC with standard tissue. But some antibodies of this format need further dilution for IHC. This is mentioned on the datasheet.

Lyophilized antibodies can be stored at 2-8°C until expiration.
Most of our liquid antibodies and reconstituted lyophilized antibodies may be stored for short term storage (up to 3 month) at 2-8°C. For long term storage we recommend to store the antibody at -20°C in aliquots. Please avoid freeze and thaw cycles.
Most of our conjugated antibodies should be stored at 2-8°C.
The individual storage conditions are mentioned on the datasheet.

anti-Lamin mouse monoclonal, X167, lyophilized, purified
Cat. No: 61047B
  • Mouse monoclonal
  • Suitable for ICC/IF, IHC and WB
  • Reacts with bovine, human, mouse, rat, rat kangaroo and trout
  • Isotype: IgG1

$251.00*
anti-Lamin mouse monoclonal, X67, lyophilized, purified
Cat. No: 61047A
  • Mouse monoclonal
  • Suitable for ICC/IF, IHC and WB
  • Reacts with bovine, human, trout and xenopus
  • Isotype: IgG1

$251.00*
anti-Lamin B mouse monoclonal, X223, lyophilized, purified
Cat. No: 61047C
  • Mouse monoclonal
  • Suitable for ICC/IF, IHC and WB
  • Reacts with bovine, human, mouse, rat, rat kangaroo and trout
  • Isotype: IgG1

$251.00*