Disease related

anti-C/EBP-beta mouse monoclonal, EBP-333, purified

Cat. No: 691625

Available, delivery time 1-7 days

$425.00*

Key Features
  • Mouse monoclonal
  • Suitable for IHC and WB
  • Reacts with human
  • Isotype: IgM lambda
Product description
Quantity 1 ml (100 µg/ml)
Antibody Type Monoclonal
Host Mouse
Isotype IgM lambda
Conjugate Unconjugated
Application IHC, WB
Purification Affinity chromatography
Reactivity Human
Storage 2-8°C
Intended use Research use only
Clone EBP-333
Immunogen Human C/EBP-beta recombinant protein
Concentration 100 µg/ml
Formulation PBS with 0.02% sodium azide
UniprotID P17676 (Human)
Synonym CCAAT/enhancer-binding protein beta, C/EBP beta, Liver activator protein, LAP, Liver-enriched inhibitory protein, LIP, Nuclear factor NF-IL6, Transcription factor 5, TCF-5, CEBPB, TCF5, PP9092
Applications
Tested applications Tested dilutions
Immunohistochemistry (IHC) - frozen 1:50-1:100 (1-2 µg/ml)
Western Blot (WB) 1:50-1:100 (1-2 µg/ml)
Background

EBP-333 reacts with C/EBP-beta or CCAAAT/enhancer-binding protein beta, a transcription factor which is not only critical for normal macrophage functioning and differentiation, but affects a variety of other factors as well, such as cytokines (IL-6; IL-4; IL-5 and TNF-alpha), neurotransmitters and other neuronal factors and processes like muscle repair and the development of multi drug resistance in tumors (P-glycoprotein). Observations have implied that manipulation of the transcription factors involved may make it possible to modulate multidrug resistance, while leaving normal function of P-glycoprotein intact.

Positive control: macrophages.

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