Disease related

anti-CD71 mouse monoclonal, EBS-CD-040, purified

Cat. No: 691602

Available, delivery time 1-7 days

$425.00*

Key Features
  • Mouse monoclonal
  • Suitable for FACS, ICC/IF, IHC and WB
  • Reacts with human
  • Isotype: IgG1 kappa
Product description
Quantity 1 ml (100 µg/ml)
Antibody Type Monoclonal
Host Mouse
Isotype IgG1 kappa
Conjugate Unconjugated
Application FACS, ICC/IF, IHC, WB
Purification Affinity chromatography
Reactivity Human
Storage 2-8°C
Intended use Research use only
Clone EBS-CD-040
Immunogen Human thymocytes
Concentration 100 µg/ml
Formulation PBS with 0.02% sodium azide
UniprotID P02786 (Human)
Synonym Transferrin receptor protein 1, TR, TfR, TfR1, Trfr, T9, p90, CD antigen CD71 [Cleaved into: Transferrin receptor protein 1, serum form, sTfR], TFRC
Applications
Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) 1:100-1:200 (0.5-1.0 µg/ml)
Immunohistochemistry (IHC) - frozen 1:50-1:100 (1-2 µg/ml)
Flow Cytometry (FACS) 0.5-1.0 µg/million cells in 0.1 ml
Western Blot (WB) 1:50-1:100 (1-2 µg/ml)
Background

The transferrin receptor is a type II membrane glycoprotein existing as a homodimer of 180-190 kDa with interchain disculphide bonding. The ligand is the serum iron transport protein transferrin. CD71 is expressed weakly on all resting leucocytes, but is upregulated on all cells upon activation, reflecting the iron dependence of proliferation. In other tissues CD71 is expressed on most dividing cells, but also strongly on brain endothelium and alveolar macrophage. CD71 expression can reflect clinical behaviour or response to therapy in a number of malignancies including leukemia, lymphoma and breast cancer.

Positive control: CCRF-CEM, Jurkat, K-562, human placenta, breast carcinoma.

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