Disease related

anti-Lamin A + C mouse monoclonal, R27, supernatant

Cat. No: 651138

Available, delivery time 1-7 days

$245.00*

Key Features
  • Mouse monoclonal
  • Suitable for ICC/IF and WB
  • Reacts with bovine, human, mouse, trout, xenopus and zebrafish
  • Isotype: IgM
Product description
Quantity 5 ml
Antibody Type Monoclonal
Host Mouse
Isotype IgM
Conjugate Unconjugated
Application ICC/IF, WB
Purification Hybridoma cell culture supernatant
Reactivity Bovine, Human, Mouse, Trout, Xenopus, Zebrafish
Storage Short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles
Intended use Research use only
Clone R27
Immunogen Nuclear pore complex-lamina fraction of bovine liver
Formulation Contains 0.09% sodium azide
Applications
Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) Ready-to-use
Western Blot (WB) Assay dependent
Background

The monoclonal antibody decorates the lamina, i.e. the nucleoplasmic layer coating the nuclear envelope.
Mutations in lamin A have been shown to cause Hutchinson-Gilford progeria syndrome in human and mouse and other laminopathies (for review see Burke & Stewart, 2002).

Polypeptides reacting: Lamin isotypes A and C (Mr 60 - 75 kDa); meiotic lamin C2

Reactivity in cultured cell lines: RV-SMC (rat vascular smooth muscle cells)















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anti-Lamin mouse monoclonal, X167, lyophilized, purified
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  • Mouse monoclonal
  • Suitable for ICC/IF, IHC and WB
  • Reacts with bovine, human, mouse, rat, rat kangaroo and trout
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anti-Lamin B mouse monoclonal, X223, lyophilized, purified
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  • Suitable for ICC/IF, IHC and WB
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$251.00*