Disease related

anti-Lassa Virus GP1 mouse monoclonal, EBS-I-301, purified

Cat. No: 691650

Available, delivery time 1-7 days

$425.00*

Key Features
  • Mouse monoclonal
  • Suitable for ELISA, ICC/IF, IHC and WB
  • Reacts with Lassa Virus
  • Isotype: IgG1 kappa
Product description
Quantity 1 ml (100 µg/ml)
Antibody Type Monoclonal
Host Mouse
Isotype IgG1 kappa
Conjugate Unconjugated
Application ELISA, ICC/IF, IHC, WB
Purification Affinity chromatography
Reactivity Lassa virus
Storage 2-8°C
Intended use Research use only
Clone EBS-I-301
Immunogen Gamma rays inactivated strain LASV
Concentration 100 µg/ml
Formulation PBS with 0.02% sodium azide
Applications
Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) 1:100-1:200 (0.5-1.0 µg/ml)
Immunohistochemistry (IHC) - frozen 1:50-1:100 (1-2 µg/ml)
ELISA Assay dependent
Western Blot (WB) 1:50-1:100 (1-2 µg/ml)
Background

Lassa virus is a member of the Arenaviridae and causes Lassa fever in predominantly West Afrika. The main reservoir is formed by local rodents. Up to half a million people are estimated to attract the disease yearly and mortality rates may reach as much as 50%. Viral proteins, coded within two ambisense RNA strands, include GP1, GP2, NP, polymerase and Z matrix protein. EBS-I-301 reacts with GP1, which is thought to bind to the host cell alpha-dystroglycan receptor. Reactivity of EBS-I-301 is confined to isolates from Sierra Leone, Guinea and part of Liberia. Nigerian and South African isolates are usually not identified by this antibody. The epitope is different from the epitope recognized by the GP1 antibody EBS-I-302.

Posisitve control: cells, serum or tissues infected with Lassa virus.

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