Disease related

anti-Desmoplakin 1/2 mouse monoclonal, DP I/II 236.23.1, supernatant

Cat. No: 651109

Available, delivery time 1-7 days

$334.00*

Key Features
  • Mouse monoclonal
  • Suitable for ICC/IF, IHC and WB
  • Reacts with bovine, human and mouse
  • Isotype: IgG2b
Product description
Quantity 5 ml
Antibody Type Monoclonal
Host Mouse
Isotype IgG2b
Conjugate Unconjugated
Application ICC/IF, IHC, WB
Purification Hybridoma cell culture supernatant
Reactivity Bovine, Human, Mouse
Storage Short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles
Intended use Research use only
Clone DP I/II 236.23.1
Immunogen C-terminal polypeptide of recombinant human desmoplakin (starting at amino acid position 1980)
Formulation Contains 0.09% sodium azide
UniprotID A0A3Q1MR22 (Bovine),P15924 (Human),E9Q557 (Mouse)
Synonym Desmoplakin, DP, 250/210 kDa paraneoplastic pemphigus antigen, DSP
Applications
Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) Assay dependent
Immunohistochemistry (IHC) - frozen Ready-to-use
Immunohistochemistry (IHC) - paraffin Ready-to-use (microwave treatment recommended)
Western Blot (WB) Assay dependent
Background

The antibody shows distinct punctate membrane staining of different epithelia. Desmosomes of the myocardium are also positive. Tumors specifically detected: primary and metastatic carcinoma and meningioma. Polypeptides reacting: desmoplakin 1 and 2 (Mr 250,000 and 215,000).

Reactivity on cultured cell lines: several human carcinoma cell lines: MCF-7,A-431, HaCaT, CaCo2; bovine cells: MDBK, BMGE.

References/Publications (3)
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